The PIK3CG Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to p110gamma, PI3Kgamma, PIK3, and PIK3CG. This antibody recognizes Human antigen. The PIK3CG Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
PIK3CG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias